Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist in our Cambridge, MA office.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Here, you will be a vital contributor to our inspiring, bold mission.
Process Chemistry & Development (PCD) is responsible for the development of robust and cost-effective processes for the manufacture of new small molecule pharmaceuticals, along with methods for achieving and controlling high standards of purity and quality.
As a Scientist working on the Process Chemistry Development (PCD) team, you will be empowered to push the boundaries of synthetic chemistryand innovate in drug development, and a typical day will include:
Designing and obtaining laboratory proof of concept for new, concise synthetic routes to challenging drug substance targets
Developing safe, efficient and robust chemical processes for drug substance manufacture
Partnering with our Pharmaceutical Sciences colleagues and our external supply chain to bring new experimental medicines to the clinic
Working in a highly collaborative and empowering environment on stimulating scientific and technical problems
Provides theoretical/conceptual input to the design, development and execution of research assignments for a specific project or projects within the functional area.
Independently plans and executes most unit operation characterization and optimization experiments within expertise and develops an awareness of unit operations in other areas.
Responsible for significant or sole technical leadership within project or complex study.
Prepares technology transfer documentation and regulatory documents or coordinates with team members to ensure execution.
Represents PCD line function on cross-functional project teams as appropriate/necessary.
Proactively identifies process or study issues/challenges and proposes potential resolutions.
Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders
Provides technical leadership to project teams within area of expertise and commits resources to execute specific project tasks.
Contributes significantly and independently to project work which may include multiple projects within functional area.
Reviews, interprets and communicates data cross-functionally within CMC and/or project teams.
Plans and implements resolutions to technical problems/issues
Represents functional area on cross-functional project teams by communicating activities from designated functional area to project team
Supports local and global initiatives which may include leading initiatives or work streams
Serves as a technical resource for junior staff and leverages expertise in laboratory technology as a functional resource/trainer.
Independently designs and executes experiments, and reports results
Assists with development of project strategy and communicates complex data/decisions within department and cross functionally as necessary
Builds and maintains relationships with key vendors and assists with technical aspects of vendor negotiations
Proactively analyses manufacturing issues and coordinates potential resolution with the CMC team.
Responsible for integrating scientific/technical efforts around cross-functional issues
EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:
Education and Experience: Required:
PhD in Chemistry; 0+ years relevant industry experience
Masters degree in chemistry and 6+ years relevant industry experience
Bachelors degree in chemistry and 8+ years relevant industry experience
Demonstrated mastery of subject or area related to field
Knowledge and Skills:
In depth knowledge of modern synthetic organic chemistry.
Advanced proficiency in route scouting, reaction optimization, synthetic methodology development, and/or elucidation of mechanism.
Proficiency with analytical tools (e.g. HPLC, GC, NMR, UV, IR, MS, etc.)
Proficiency with utilizing typical literature searching techniques to solve organic chemistry problems
Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
Teamwork -- Ability to work well in highly cross functional team environment and across global line functions.
Communication Skills -Able to expresses one’s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents
Organization – Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
Resource Management -Ability to manage one’s time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
External Involvement – Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events
Technical - Subject matter expertise and knowledge of applicable lab equipment and operations
May require approximately 5-10% travel.
WHAT TAKEDA CAN OFFER YOU:
401(k) with company match and Annual Retirement Contribution Plan
Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days