TIGL Research Technician at Dana-Farber Cancer Institute in Boston, Massachusetts

Posted in Other 17 days ago.





Job Description:


Job ID:22827

Location:450 Brookline Ave,

Boston,
MA 02215


Category:Research Technician/Scientist

Employment Type:Full time


Overview


The Dana Farber Cancer Institute (DFCI) brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Translational Immunogenomics Lab (TIGL) within DFCI uses state-of-the-art genomic technologies to assess the response of the immune system to cancer and therapy. TIGL evaluates the latest developments in the field, implements the optimal methods for the task at hand, and invents methods when current approaches are inadequate. The current focus of TIGL is discovering patient-specific neoantigens, understanding the details and consequences of interactions between neoantigens and T cells, and applying this knowledge to support neoantigen immunization therapy.

This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.





Requirements


A full-time position is available for a highly motivated research technician to join theTranslational Immunogenomics Lab (TIGL) team. Work tasks will include:


  • Preparing and sequencing libraries from single-cell and bulk RNA

  • Preparing and sequencing libraries that combine analysis of DNA, RNA, and/or protein

  • Performing single-cell qPCR assays for RNA expression, genotyping, and splicing variants

  • Generating plasmid constructs for mammalian expression

  • Preparing reagents and media used in lab experiments

  • Operating and maintaining lab equipment

Training is available in all procedures; some experience in the above techniques is preferred.

We are looking for candidates who have at least two years of availability. The job will provide great exposure to someone who is considering going to graduate school or medical school in the future.


  • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.

  • Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.

  • Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.

  • Isolate, identify and prepare specimens for examination.

  • Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff.

  • Participate in grant application process and manuscript preparation as required.

  • Maintains detailed notebook of all work-related activities.

  • Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.

  • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.

  • May be responsible for the development, modification and improvement of standard operating procedures.

  • Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.

  • May be responsible for designing and executing advanced experiments and setting strategy.

  • May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.

  • May be responsible for monitoring laboratory budgets.




Qualifications


Education and Experience


  • Minimum of B.A./B.S. with experience in molecular biology. Major in biology or chemistry is preferred.

  • Some previous laboratory experience is required.

Knowledge/Skills/Abilities


  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.

  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.

  • Ability to analyze information and use logic to address work-related issues and problems.

  • Must have attention to detail, meticulous record-keeping skills, and be thorough in completing work tasks.

  • Ability to work within a team environment.


  • Bachelor's Degree required with a major in biology or chemistry preferred.

  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.

  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.

  • Ability to analyze information and use logic to address work-related issues and problems.

  • Must have attention to detail and be thorough in completing work tasks.

  • Ability to work within a team environment.


Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.



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Job ID:22827

Location:450 Brookline Ave,

Boston,
MA 02215


Category:Research Technician/Scientist

Employment Type:Full time