Sr Scientist, Chemistry (Medicinal Chemistry) at PTC Therapeutics, Inc. in Bridgewater, New Jersey

Job Description:

Job Description Summary:

The Senior Scientist, Chemistry contributes to PTC’s drug discovery efforts by synthesizing small molecules in support of internal lead optimization programs. The incumbent is responsible for independently planning and executing synthetic organic chemistry protocols to efficiently obtain desired targets for biological assays.

The selected candidate is also responsible for interpreting and communicating experimental results to his/her supervisor and the project team.

Job Description:

Primary duties/responsibilities:

• Independently plans, initiates, and executes synthetic organic chemistry experiments and interprets and communicates results as part of a multi-disciplinary team.




• Maintains broad knowledge of state-of-the-art principles and theories related to synthetic organic chemistry and medicinal chemistry.




• Contributes to the strategy and direction of successful drug discovery programs.




• Manages and directs the efforts of chemists at contract research organization (CRO)




• Presents findings internally and externally to cross-functional teams.




• Participates in the development and writing of patent applications and identifies patentable inventions.




• Abides by all safety and regulatory guidelines.




• Maintains a detailed laboratory notebook.




• Performs other tasks as assigned.

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

• Track record of consistent and successful drug discovery accomplishments (e.g., patent inventorship, conference presentations, and peer-reviewed publications).




• Deep understanding of synthetic and medicinal and chemistry concepts with high lab productivity.




• Experience with designing medicinal chemistry strategies to optimize characteristics of hit molecules (e.g. potency, solubility, stability, absorption, etc.) to generate lead series and eventual clinical candidates.




• Strong communication skills.




• Ability to work collaboratively in a fast-paced, matrixed, team environment.




• Excellent planning, organization, and time management skills.

* Minimum level of education and years of relevant work experience.

• Ph.D. degree in a scientific discipline preferably in Organic Chemistry with a minimum of 5 years’ relevant experience in the Pharmaceutical/Biotech Industry

* Travel requirements

 Up to 10%

**At PTC Therapeutics we are seeking candidates in the United States who are fully vaccinated against COVID-19 or who will be fully vaccinated by the time they begin the position.

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

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