Commensal bacteria constituting the microbiome impact human health in a variety of ways. The Duchossois Family Institute (DFI) is investigating how the microbiome enhances resistance to diseases by performing genomic and metabolomic analyses on a wide range of commensal bacteria derived from healthy humans. Laboratory studies in the DFI currently focus on dissecting the competitive and symbiotic interactions between commensal bacteria, in the process generating massive amounts of data that require computational and system biology platforms for analysis.
The job manages a team of professional staff responsible for scientific research projects and research facilities. Ensures compliance of research activities with institutional, state, and federal regulatory policies, procedures, directives, and mandates. Manages the production of articles, reports, and manuscripts, and presents research findings at meetings and/ or conferences.
Provides leadership and oversight of internal projects to ensure proper planning, execution, and completion of microbiome related research.
Develop and validate new laboratory research methods in the areas of defined gut microbiome medium, sporulation and germination characterization and lyophilization of viable bacterial strains.
Maintain thorough documentation for all work performed across all projects and provide full accounting and verification records for clients and projects.
Supervisory duties including training and guiding laboratory staff; assisting in developing policies, procedures and/or methods for laboratory experimentation.
Interface and work with staff in the DFI current Good Manufacturing Practices (cGMP) facility at the University of Chicago to optimize culturing, lyophilization and preparation of live biotherapeutic products that are selected from the DFI Symbiotic Bacterial Strain Bank.
Manages research professionals and support staff involved with planning, monitoring, and compliance aspects of research projects. Advises other researchers on long-range plans for research projects.
Develops goals and operating procedures, practices, and guidelines for research activity based on department strategy.
Manages the laboratory facilities, including the purchase of new equipment and the maintenance and repair of laboratory equipment.
Reviews research of others, and may conduct own research, in area of expertise. Edits and approves articles, reports and manuscripts. Presents research findings at meetings and/or conference. Manages the research of processes in clinical or non-clinical settings. Program and use computers to store, process, and analyze data.
Performs other related work as needed.
Minimum requirements include a college or university degree in related field.
--- Work Experience:
Minimum requirements include knowledge and skills developed through 7+ years of work experience in a related job discipline.
PhD in Microbiology
Experience in laboratory management, mentorship, and/or leading a technical team.
Experience cultivating, characterizing, and preserving anaerobic microorganisms.
Experience working in and maintaining anaerobic chambers and glove boxes.
Experience in bacterial kinetics and microscopy.
Experience working in a cGMP environment.
Extensive knowledge in microbiological techniques and methodology.
Excellent record keeping and organizational skills.
Knowledge of regulatory policies and procedures.
Quantitative and analytical skills.
Strong verbal and written communication skills.
Excellent time-management skills.
Ability to work independently and as part of a team.
Proficiency with electronic lab inventory systems, databases, Excel, PowerPoint.
Familiarity with bioinformatic tools (e.g. R-script).
Must have physical ability to move compressed gas cylinders
Cover Letter (preferred)
When applying, the document(s) MUSTbe uploaded via the My Experience page, in the section titled Application Documents of the application.
Scheduled Weekly Hours
COVID-19 Vaccination or Approved Medical or Religious Exemption Required
Drug Test Required
Health Screen Required
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