New Technology Lead, Global Gene Therapy at Takeda Development Center Americas, Inc. in Cambridge, Massachusetts

Job Description:

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Job Description

Are you looking for a patient-focused company that enables transformative technologies to address patients' needs while inspiring you and support your career? Takeda is a world-class organization where we combine our expertise in disease biology, modality technologies and drug development experience to develop gene therapies in a holistic approach. We are looking for someone with substantial experience in vector design and gene therapy drug development experience to join Takeda to grow our gene therapy research effort. Be empowered and join us as a Gene Therapy Technology Lead in the Global Gene Therapy Research Team.

As the Gene Therapy Technology Lead, you will be responsible and accountable for leading technical advancement of the Gene Therapy team to test GT components internally and through external collaborations to expand the current gene therapy capabilities.

ACCOUNTABILITIES

• Experience with new technologies that promote gene therapy drug development, including viral or non-viral gene delivery systems with insertional and gene editing technologies.


• Mechanistic study-driven approach to work with others internally and with CROs to implement experiments.


• Represent internal team and work with external academic and industrial collaborators to evaluate and improve new technologies.


• Execute newly designed assays and experiments to screen potential gene therapy candidates. Knowledge and protocol transfer to associates (internally and to CROs) to complete experiments for sample analysis.


• Independently design scientific research projects, analyzes and presents experimental data.


• Contribute to the strategy for the project and lead communications with sub-groups within GGT and other research line team members.


• Be the gene editing lead in project teams and works across sub-groups within Global Gene Therapy and beyond including all Drug Discovery Units (RD, NS, GI & ONC) and Preclinical and Translational Sciences (Toxicology, DMPK and more).


• Follow compliance of documentation in electronic lab notebook and author scientific reports that supports internal documentation and regulatory submissions.

• PhD degree in a scientific discipline with 6+ years experience


• Experience in gene transfer and gene editing mechanisms and components. Design gene expression cassette suitable gene delivery.


• Experience using DNA and protein sequence analysis software to design candidates in silico.


• Experience with gene delivery and gene editing in human hemetopoetic stem cells and linages of cell types and other organs is desirable.


• Experience progressing discovery and preclinical programs in an industry setting


• Follow compliance of documentation in electronic lab notebook and author scientific reports that supports internal documentation and regulatory submissions.

Absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. US field-based employees must be fully vaccinated as a condition of employment, absent an approved religious or medical reason. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. If you are contacted by a Takeda recruiter about your job application, we encourage you to seek more information on the applicable guidelines for the Business Unit/Function to which you have applied.

Employee may also be eligible for Short-term and Long-term incentive benefits. Employees are eligible to participate in Medical, Dental. Vision, Life Insurance, 401(k), Charitable Contribution Match, Company Holidays, Personal & Vacation Days, Student Loan Repayment Program and Paid Volunteer Time Off. If candidate is not eligible for any benefits or other comp., those can be excluded.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

USA - MA - Cambridge - Binney St

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time