Downstream Engineer III at Millipore Corporation in Bedford, Massachusetts

Job Description:

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences.


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Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to bring their curiosity to life!



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If you are a resident of a Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.



Your Role



We are seeking an experienced and highly motivated Engineer to join the company as a Downstream Engineer III, a critical role within the BioContinuum™ Platform Applications & Innovation team. This team is working at bench-scale, leading the evolution and convergence of process, analytical, and digital technologies to pioneer a facility of the future for continuous biomanufacturing. As an integral team member, you will drive the development of intensified processes through the design and execution of lab- and pilot-based experimental work in the areas of advanced downstream processing, including connection of downstream purification trains to perfusion production processes, continuous chromatography and filtration operations, and advanced control methods utilizing next generation sensors.


You will help shape our downstream strategy in intensified and continuous biomanufacturing by leveraging your industrial experience and understanding of manufacturing pain points and bottlenecks to propose new project concepts, to align objectives and project plans with key stakeholders, and to execute on project plans. Finally, you will disseminate key experimental results by supporting internal and external thought leadership activities.



Who You Are:




Minimum Qualifications:

• Bachelor's Degree in Chemical or Biochemical Engineering with 5+ years of biotech experience; or Master's Degree in Chemical or Biochemical Engineering with 3+ years of biotech experience; or PhD in Chemical Engineering or Biochemical Engineering.


• 1+ year experience applying chromatography theory to the hands-on development and optimization of protein purification processes via chromatographic separations

Preferred Qualifications:

• Strong background and practical hands-on experience with purification and product quality analytical techniques, particularly for CHO cell-based processes and monoclonal antibodies


• Experience operating small and large-scale protein purification systems, including clarification, chromatography, filtration, and other unit operations, including the development of automation and control strategies


• Experience in statistical design of experiments (DoE) coupled with strong analytical and problem-solving skills; ability to solve problems creatively and contribute to innovation in product and process development


• Ability to manage multiple projects simultaneously to meet project deliverables and timelines


• Excellent verbal and written communication skills, ability to present at internal and external meetings and produce publication-quality documentation


• Proven track record as a committed team player with the ability to work on multi-disciplinary teams in a matrix environment


• Experience with continuous bioprocessing operations

• Experience with lab-based automation and data processing software such as LabView and MATLAB is a plus


• Experience with on-line/at-line analytics (ie spectroscopy, HPLC, automated sampling) is a plus


• Working knowledge of pharmaceutical/biotechnology regulatory and quality issues including GMP regulations and QbD principles is a plus

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.


As an employee of the Company, you will be required to comply with all of the Company's COVID-19 safety protocols and policies. The organization has currently suspended enforcement of its COVID-19 Vaccination Policy, but that policy may be reinstated by the Company in its discretion.


Job Requisition ID: 246206


Location: Bedford


Career Level: D - Professional (4-9 years)


Working time model: full-time Apply Now