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Associate Director, Pharmacology at PTC Therapeutics, Inc.

Posted in Science 30+ days ago.

This job brought to you by eQuest

Type: Full-Time
Location: SOUTH PLAINFIELD, New Jersey

Job Description:

Job Description Summary:

The Associate Director, Pharmacology is responsible for supporting efforts to identify and implement biomarkers to be used in clinical trials for oncology and rare genetic disorders. This may require overseeing both the in-vivo models of efficacy as well as in-vitro work to develop an assay.

The Associate Director, Pharmacology supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.


Job Description:


Primary duties/responsibilities:

  • Plans, initiates, directs and executes preclinical research and experiments and interprets and communicates results as part of multi-disciplinary team(s) results.  These studies will correlate functional effects in mouse models of disease to measurable biomarkers.

  • Work with CROs to optimize and develop assays.  Some assays may need to be developed and run under GCP conditions.

  • Work with clinical investigators to implement biomarkers in clinical trials and provide operational support.

  • Develops and writes protocols, study reports and relevant sections of IND documents as appropriate.

  • Maintains appropriate state-of-the-art principles and theories and identifies new technologies.

  • Abides by all IACUC requirements.

  • Abides by all safety requirements.

  • Supervises the activities of other personnel or assumes the role of project leader to lead a team on a special project(s).

  • Contributes to general lab needs such as:

    • Equipment maintenance.

    • Capital equipment purchases.

    • Participates in hiring decisions

  • Performs other tasks as assigned.


Minimum level of education and years of relevant work experience:

  • PhD degree in a Biological life sciences discipline, and a minimum of 7 years of relevant, progressively responsible experience in a pharmaceutical, biotechnology or related environment.  Experience must include expertise in developing assays using immunological methods to measure proteins (ECL, IHC), genomics, and mRNA (RNAseq, qPCRP, Nanostring). 

Special knowledge or skills needed and/or licenses or certificates required:

  • Strong writing and oral communication skills.

  • Demonstrated ability to work effectively in a multi-disciplinary team environment.

  • Attention to detail.

  • Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.

Special knowledge or skills and/or licenses or certificates preferred:

  • Pharmacology expertise in oncology, neurology or rare diseases

  • Experience in the developing of FDA submissions

Travel requirements


Laboratory based position

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

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