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Sr. Scientist, Process Development at US03 Lonza Walkersville Inc. in Houston, Texas

Posted in Science 30+ days ago.

This job brought to you by eQuest

Type: Full-Time

Job Description:


Today Lonza is a global leader in life sciences. We are more than 15,000 employees in more than 100 locations around the world. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Lonza in Houston, TX (Pearland) is looking for an experienced Process Development Senior Scientist.  The Process Development Senior Scientist will be experienced in development and optimization of cell culture processes or analytical methods for the production of cell and gene therapy products. The successful candidate should have experience with primary cell and tissue isolation techniques, maintenance, expansion, and differentiation of stem cells including pluripotent stem cells, in vitro culture of T cells and/or primary cells derived from human tissue, in vitro culture of adherent and suspension cell lines, gene modification and transfection / transduction techniques, downstream and fill/finish processing, and analytical methods and testing.

Key responsibilities:

  • Responsible for successful development and execution of state-of-the-art manufacturing processes for Current General manufacturing Practices (cGMP)within the Cell Therapy Development matrix.

  • Understand cell-based assays including, but not limited to, morphological assessment, functional differentiation, detection of marker expression, Flow Cytometry and Quantitative Polymerase Chain Reaction

  • Interact with new or existing Cell and Gene Therapy clients to document and transfer new processes to Lonza sites and communicate and present the work in internal and client meetings

  • Lead and support scientific or engineering expertise toward the design and development of new process ideas that support client product concepts

Key requirements:

  • PhD in Life Sciences with focus on biology or Bioengineering with significant years of related manufacturing, process development experience in biotech industry experience; MS degree in Life Sciences field with substantial years of related manufacturing, process development experience in biotech industry

  • Experience with a variety of cell culture systems and optimization of cell expansion and differentiation process

  • Experience or knowledge of analytical methods and in process controls commonly used in manufacturing processes such as cell count viability, flow cytometry, and molecular biology techniques

  • Experience with development of bioreactor protocols and scale up studies for mammalian cells or stem cells is highly desirable

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.