Sr. Associate Scientist/Engineer III, Technical Development at Biogen in Research Triangle Park, North Carolina

Posted in Other 4 days ago.

Type: Full Time





Job Description:

Job DescriptionThis senior associate scientist role in the ASO TD group is responsible for all aspects of purification development of ASOs including process development, process characterization, scale-up, assessing process risk, for all unit operations (chromatography, detritylation, UF/DF). This position is expected to understand the interrelationships between process development, manufacturing and quality aspects of the project including reviewing/analyzing technical data and documents, manufacturing records and assisting in solving more complex problems, provide manufacturing support and authoring CMC section of INDs/NDAs. This position acts as a subject matter expert on purification processes to facilitate interactions internally within the ASO organization (synthesis, drug product, analytical) as well as cross functionally (with manufacturing/Manufacturing Science tech transfer teams, Reg-CMC and Quality). Mentoring others in the lab, evaluating new technologies and equipment, identifying, and solving problems, the ability to work innovatively, and independently are key responsibilities of this position. This position can be based in Cambridge or in our Research Triangle Park location.Qualifications4-6+ years (w/BS) or 2-4+ years (w/MS) experience in purification process development, either in an academic and/or industrial environment, developing processes for proteins and/or antisense oligonucleotides. Strong analytical skills and experience in writing reports and presenting technical data are also requirements.Education:MS/BS in Biochemistry, Chemical Engineering, or related scienceAdditional InformationThis senior associate scientist role in the ASO TD group is responsible for all aspects of purification development of ASOs including process development, process characterization, scale-up, assessing process risk, for all unit operations (chromatography, detritylation, UF/DF). This position is expected to understand the interrelationships between process development, manufacturing and quality aspects of the project including reviewing/analyzing technical data and documents, manufacturing records and assisting in solving more complex problems, provide manufacturing support and authoring CMC section of INDs/NDAs. This position acts as a subject matter expert on purification processes to facilitate interactions internally within the ASO organization (synthesis, drug product, analytical) as well as cross functionally (with manufacturing/Manufacturing Science tech transfer teams, Reg-CMC and Quality).PDN-91c440e2-cb2a-4dc4-8f3b-19e46819b8b9