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Senior Manager Technical Operations at ALDEVRON MADISON, LLC in Madison, Wisconsin

Posted in Management 30+ days ago.

Type: Full-Time

Job Description:

The Sr Manager, Technical Operations is an innovative scientific leader that is able to effectively lead a skilled scientific team. She/he is a technical subject matter expert (SME) in the areas of product development, manufacturing process development and analytical method development that provides scientific support for internal and external discussions.


  • Manage daily activities and serve as the technical SME of a scientific team that is focused on product development and complex process development projects

  • Provide technical guidance for method development and optimization for Upstream Processing, Down Stream Processing and Analytical Method Development

  • Lead product development function working closely with scientists, Product Management, Clients and R&D colleagues

  • Client centric leader focused on creating a great experience for clients with on-time completion of projects and providing technical guidance for internal and external communications

  • Translate project proposals into detailed work plans; present team members with work plans, ensuring that they have information and resources necessary for successful execution of the project

  • Assist Aldevron’s Client Relations (Technical Sales) Team with review of project opportunities and development of project proposals

  • Serve as technical SME during client calls, pre and post purchase order

  • Develop direct reports so they can assist in scientific support of client projects including serving as technical SME on client calls

  • Accountable for technology transfer of manufacturing and analytical test methods from Aldevron’s research-grade laboratories to Aldevron’s GMP laboratories

  • Support transfer of manufacturing and analytical test methods from small-scale development to large-scale manufacturing

Required Skills

  • Protein expression optimization experience using various constructs, host systems, equipment over a range of protein classes

  • Purification of recombinant proteins using all common chromatography modes at the mg to multi-gram scale

  • Experience in process engineering to support effective transfer to manufacturing

  • Expertise with the AKTA purification platform, including the Unicorn software package, ideally with experience from AKTA 25 through AKTA Pilot

  • Expertise with protein analytical methods, including HPLC analysis (RP-HPLC, aSEC, and analytical ion exchange), in vitro enzymatic activity measurements, western blotting, and SDS-PAGE


  • Below education and combined years of work experience in the field of protein biochemistry or closely related field:

    • B.S./B.A. and 20+ years

    • M.S. and 15+ years

    • PhD and 10+ years 

  • Prior management of a biotechnology laboratory team is required

Work Hours/Shift

Monday-Friday – 8 am – 5 pm

Join Us Today!

Join a team committed to making lives better. Aldevron provides high-quality plasmid DNA, proteins, enzymes, antibodies, and other biologics to help our partners achieve significant breakthroughs for a variety of life science applications.

If you would like to thank someone for referring you to this role, please apply at, and include their first and last name as a referral source!

Aldevron is committed to equal opportunity for all employees and applicants. We are committed to creating a diverse workforce and consider all qualified applicants without regard to race, religion, color, sex, national origin, age, sexual orientation, gender identify, or protected veteran status among other factors.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)

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