Exciting research opportunity in the Moskowitz laboratory to help drive a research project in developmental biology aimed to understand the molecular basis of birth defects. The lab is devoted to the genetic, genomic and molecular study of gene regulatory networks in developing organs, particularly cardiac development with respect to Congenital Heart Disease (CHD). In cardiac development, we have identified an essential role for cilia-based Hedgehog signaling in cardiac progenitors, an essential aspect of mammalian cardiac development. Our studies have contributed to a paradigm shift in the understanding of cardiac morphogenesis, which is driven by events in cardiac progenitors rather than in the heart itself (e.g. Hoffmann et al., 2009; Xie et al., 2012; Zhou et al., 2017). We have recently identified a surprising and novel role for Hedgehog signaling in developmental timing control that will be the basis of future projects (Rowton et al. 2020).
The job develops and implements programs to promote a research project or contributes to the scientific direction of a research resource.
This position is wholly funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.
Serves as a resource for collecting data and performing analysis. Facilitates and promotes a research project by providing scientific or intellectual information.
Develops laboratory protocols and training on new techniques. Manage, analyze and make recommendations on complex data sets for research.
Creates first drafts for scientific writing and publications, including protocols and grants.
Trains and mentors laboratory personnel.
Performs other related work as needed
Minimum requirements include a PhD in related field.
--- Work Experience:
Minimum requirements include knowledge and skills developed through 5-7 years of work experience in a related job discipline.
ChIP-seq, ATAC-seq, GRO-seq, RNA-seq, and Bru-seq
CRISPR genetic engineering
Rapid protein degradation using Degree system
Cardiac functional analyses
Cell culture experience
Protein-protein interaction analysis using mass-spectrometry
Cover Letter (required)
When applying, the document(s) MUSTbe uploaded via the My Experience page, in the section titled Application Documents of the application.
Scheduled Weekly Hours
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Drug Test Required
Health Screen Required
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