Job Description:

Senior Scientist II, In Vivo Ocular Pharmacology

Job LocationsUS-MA-Watertown Job ID2024-1385

Overview

Be Seen and Heard at EyePoint Pharmaceuticals

At EyePoint, leadership trusts our employees to get the job done. The patient-centric and award-winning approach we're taking in business fuels our success for:

• preventing blindness through vision-saving medications
• delivering best-in-class proprietary pharmaceutical technologies
• transforming ocular drug delivery

We See You.

Your wellbeing

Your professional worth

Your future at EyePoint

EyePoint offers robust total rewards in a science-based entrepreneurial culture that empowers curiosity and innovation to help catapult your career. There's space for every voice and perspective to be heard in our on-site and remote environments where a variety of strengths and diverse backgrounds are connected.

An exciting opportunity is available for a Sr. Scientist II to join the in vivo ocular pharmacology team at EyePoint Pharmaceuticals. We are seeking a highly skilled, self-motivated and talented scientist to lead and execute in vivo preclinical research and biomarker discovery activities supporting portfolio progression. The successful candidate will work collaboratively across functions within clinical, regulatory and R&D to think strategically, lead and execute preclinical research to generate decisional data packages in support of our ocular drug discovery and development projects.

The ideal candidate will bring extensive knowledge of a wide variety of in vivo and ex vivo research methodologies and analyses and a track record of successful scientific impact in the biotechnology or pharmaceutical industry with demonstrated experience in leading and managing scientific projects from conceptualization through execution and analysis. This includes setting project goals, designing and executing on experimental strategies, managing timelines, thinking creatively of opportunities to leverage cutting-edge technologies, and coordinating with cross-functional teams to achieve milestones and deliverables.

This position is located at our Watertown, MA site.

Responsibilities

Primary responsibilities include, but are not limited to, the following:

Individual responsibilities

• Subject matter expert in nonclinical in vivo strategy to achieve strategic corporate goals and ophthalmology pipeline, collaborate with external consultants where necessary.
• Lead nonclinical in vivo studies including protocol design, study conduct and monitoring, data analysis and presentation of results across all levels of the organization.
• Collaborate with clinical team to design nonclinical studies supporting proposed clinical trials and clinical bioanalytical samples.
• Collaborate with regulatory affairs to author nonclinical sections of global regulatory submissions.
• ID, select and manage nonclinical CROs, including forecasting and management of study financials.
• Serve as nonclinical lead in Program Team meetings.
• Communicate key results to leadership.
• Author abstracts and manuscripts in collaboration with EyePoint's Early Product Commercialization team.
• Contribute to a culture that promotes continuous improvement, ownership, professional growth and inclusion.

Qualifications

Primary skills and knowledge required include, but are not limited to the following:

• 3Rs-centered, welfare-oriented approach to animal-based research.
• Hands on, in vivo experience with mouse, rat, rabbit, pig and NHP handling, dosing, anesthesia, necropsy and dissection.
• Ability to think independently and critically to design in vivo experimental strategies and analysis plans to generate robust and reproducible results in a timely manner.
• Strong technical expertise and hands-on experience leveraging standard and cutting-edge imaging technologies, data analysis software (SigmaPlot, Prism).
• Experience with both small and large molecule drug development.
• Outstanding communication skills, essential for effective collaboration with internal and external stakeholders.
• Exceptional organizational and attention to detail skills, with the capacity to work autonomously as well as in a team setting, managing complex timelines across multiple programs.
• Ability to troubleshoot and effectively solve problems, demonstrating resourcefulness and a high level of analytical thinking.
• Passion for presenting your work in internal teams, external collaborations with KOLs and at professional ophthalmology based conferences.

Level of Education Required:

PHD with 4 years of related industry experience or MS with 6 years of related industry experience leading and executing preclinical in vivo research for drug discovery and development.

Preferred Field of Study: Pharmacology, ADME, PK/PD or related field

Number of Years of Experience in the Function and in the Industry: Minimum of 6 years of pharmaceutical industry experience.

Envision Your Future

With the exciting energy of a winning culture and an exhilarating pace, we are an ophthalmology company committed to preventing blindness by developing and commercializing innovative therapeutics.

The collective power of our values influences everything we do, and everything we do for you.

• Success begins with our People
• Patients First
• Integrity
• Results-Driven
• Innovation
• Team Focus
• Diversity & Inclusion

EyePoint Pharmaceuticals is proud to be an equal opportunity employer. We believe that diversity and inclusion among our colleagues is critical to our success as a company, and we seek to recruit, develop, and retain the most talented people from a diverse candidate pool. All applicants will be considered for employment without attention to age, race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

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