Senior Scientist, Flow Cytometry at AstraZeneca in Waltham, Massachusetts

Job Description:

Our Waltham, Massachusetts facility develops life changing small-molecule and biologics research in North America, with innovative laboratories at the Gatehouse Park BioHub, just west of the city center. Our BioHub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas. Here, we play host to some of the most innovative technology and lab spaces, all crafted to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers.



Summary of the Group



The Flow Cytometry group is part of Dynamic Omics/ Centre for Genomics Research (CGR) and Discovery Sciences within AstraZeneca, and works across all therapeutic areas including Oncology; Cardiovascular, Renal and Metabolism (CVRM); Respiratory and Immunology (R&I); Vaccines and Immunotherapies (V&I); Neurosciences, and Rare Diseases. Our team supports over 450 scientists globally and delivers key data to projects across all phases of the drug discovery and development. We work across all modalities from small molecules to biologics. The Global Flow Cytometry Center of Excellence is among the leading flow cytometry organizations in the US and UK, and boasts state-of-the-art instrumentation equipped with cutting-edge technology and the requisite expertise.



What you'll do



In this role, you will support the operations of the team in Waltham, MA, and participate in collaborations with multiple therapeutic areas. In 2026, the team will relocate to Kendall Square to our new Boston R&D headquarters. The successful candidate will have the opportunity to work and grow in a fast-paced environment under the supervision of senior staff members.


In this role, you will serve as a primary resource to:


• Support multiple therapeutic areas, daily operate and maintain flow cytometers, cell sorters, ensure accurate acquisition and management of data under local and global flow cytometry leadership


• Collaborate on innovative immunology/flow cytometry projects and/or automation solutions to support Oncology within AstraZeneca


• Be an expert in multicolour flow cytometry, review and analyse data, interpret experimental results, and summarize data for presentations and reports with accountability for accuracy


• Contribute to the development of new technological platforms such as Imaging flow cytometry


•



Education & Experience Requirements:


• PhD degree (or equivalent experience) in Immunology, Bioinformatics, Engineering or a related quantitative discipline and 3+ year of relevant experience, or a Bachelor's/Masters with 5+ years of directly relevant outstanding performance


Essential Criteria


• Track record of scientific excellence in immunology, flow cytometry and/or automation


• Extensive experience in designing, leading and executing flow cytometry experiments


• High-content and/or spectral flow cytometry experience


• Experience with a variety of flow cytometry data analysis and bioinformatic tools, including FlowJo, FCS Express, OMIQ, and Cytobank


• Experience with immunology techniques


• Great teamwork and communication skills, both verbal and written


• Strong multi-tasking, time management and organizational skills


Desirable Criteria


• Flow cell sorting experience is highly desirable


• Programming skills such as Python and R are desirable


• Experience in automation is desirable


• Experience in understanding and analysing other omics data (e.g. transcriptomics, mass spec) is a plus


• Microscopy experience is desirable



AstraZeneca in Boston, MA



Our Waltham site offers a variety of amenities to help book productivity and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community.


As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here: Kendall Square Press Release


At AstraZeneca, we are on a mission to eliminate cancer as a cause of death. As part of our Oncology R&D team, you will be at the forefront of applying science to studies and using innovative approaches to create new possibilities. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique. With varied and interesting problems to solve, we get a constant thrill from the challenge. We benefit from global interactions with top experts across the world, giving us an incredible support network. By working with diverse functions, we get exposure to multidisciplinary learning and diverse perspectives.


Ready to make a difference? Apply now!


AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by ap


Why AstraZeneca


Make a significant impact to patients' lives around the globe


At AstraZeneca, we 're dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and ignite your Entrepreneurial ambitious spirit. There's no better place to make a difference in medicine, patients, and society. An inclusive culture that champions diversity and teamwork. Always committed to lifelong learning, growth, and development.


Where can I find out more?


Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/


Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/


Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.