Associate Director - Oncology Safety Pathology, Clinical Pharmacology and Safety Sciences at AstraZeneca in Gaithersburg, Maryland

Posted in Other 13 days ago.





Job Description:

Associate Director - Oncology Safety Pathology, Clinical Pharmacology and Safety Sciences



Are you a passionate veterinary anatomic pathologist interested in driving innovation in drug discovery to bring safe and effective therapies to cancer patients? This is an exciting opportunity to join a global group of highly skilled pathologists that work closely with dedicated safety teams to drive the discovery and development of innovative treatments for patients. The role is broad in scope and offers significant potential for scientific collaboration and professional development.


Join our global CPSS team as a Pathologist, where you'll collaborate with discovery safety specialists, toxicologists, and disease area scientists. You'll provide expert anatomic pathology support to drug projects across all development stages. Our pathologists are empowered by access to AI digital pathology, multiplex assays, advanced molecular imaging techniques, and a full suite of in vivo imaging technologies. This position offers the opportunity for a pathologist to explore new ways of supporting how we investigate both the safety and efficacy of drugs within our projects. The role will work within a dynamic scientific team with the opportunity to deliver scientific strategies that change our view of disease. This is an exciting opportunity for a dedicated pathologist to shine.


You'll contribute to the design and assessment of investigative safety and efficacy studies, ensuring timely delivery of impactful, decision-making pathology data. In addition, you'll provide pivotal pathology support and develop expertise in cutting edge novel treatment modalities, including T cell therapies, immune cell engagers, antibody drug conjugates and PROTACs.


Repuired Experience:
• Degree in Veterinary Medicine
• Postgraduate pathology qualification (DACVP, DECVP, FRCPath, DJSTP or equivalent


• 1-3 years research or pharmaceutical/toxicologic pathology experience - previous experience with cellular therapies would be an advantage
• Ability to integrate pathology findings with a range of additional endpoints (e.g., clinical pathology, IHC/ISH, MSI, omics data) and provide contextualized interpretation for project teams
• Highly effective written and oral communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders


Desirable Skills/Experience:
• PhD in pathology or a related discipline
• Relevant pharmaceutical experience of providing discovery and toxicologic pathology support and acting as a pathology representative on multiple drug development projects
• Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and peer review of short- and long-term toxicology studies
• Track record of scientific delivery demonstrated by peer-reviewed publications in high impact/high-quality journals
• Ability to provide a holistic view of translational safety and pathophysiology from animal to patient



If you are a veterinary anatomic pathologist seeking a new challenge, please get in touch with Kim Maratea (kim.maratea@astrazeneca.com) for an informal discussion about this exciting opportunity.



At AstraZeneca's Biopharmaceuticals R&D division, we are driven by our desire to understand and reveal new insights. We follow the science to explore and innovate, working towards treating, preventing, modifying and even curing some of the world's most complex diseases. We are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. We celebrate our successes and failures along the way. We are committed to making a difference and improving patient access to healthcare globally. Our values guide everything we do at AstraZeneca. They power our belief in What Science Can Do.


Are you ready to work with curious minds in an inclusive culture? Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. Here all doors are open, and every voice is heard. From working side-by-side with academia to innovating with biotech, we are forever expanding our horizons. By sharing and increasing our knowledge we are empowered to be the best we can be and accelerate progress.


Join us today and be part of a team that makes a bigger impact on patients' lives!


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.


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