Research Lab Tech II, Pathology at Brigham & Women's Hospital(BWH) in Boston, Massachusetts

Job Description:

GENERAL SUMMARY:


The focus of the lab is to understand intestinal barrier loss (sometimes referred to as "leaky gut") in Crohn's disease, ulcerative colitis, and other immune-mediated intestinal diseases. Ongoing projects include:


• In vitro analyses of protein interactions that modify the barrier.


• In vivo determination of barrier loss and restoration effects on disease.


• Development and testing of novel therapies.


Under supervision of PI, work independently to:


• Manage experimental mouse colony.


• Provide experimental support to other lab members.


The lab environment includes members from diverse backgrounds who collaboratively drive discovery and teach one another.


• Training in specific skills can be provided by current lab members.


• A wide range of tools are used, including genetically-modified (knockout/transgenic) mice, patient biopsies, and cutting-edge microscopy approaches.


• Continuing education occurs informally, during lab meetings and journal clubs, and through independent reading.


PRINCIPAL DUTIES AND RESPONSIBILITIES:


With increasing independence as skills are acquired:


• Manage breeding, maintenance, and records of mouse colony.


• Tag, genotype, and transfer mice for breeding, weaning, and experimental use.


• Interact with PI and others to plan and prepare for upcoming experiments.


• Ensure that all necessary supplies, including mice, are available.


Opportunities for greater experimental involvement are available commensurate with skills and interests.



Qualifications

QUALIFICATIONS:


BS in biological/physical science required.


At least one year of experience in a related research setting (for TRA II).


SKILLS/ABILITIES/COMPETENCIES REQUIRED:


• Attention to detail and accuracy.


• Ability to follow existing protocols and both learn and develop new methods


• Willingness to or experience in handling laboratory mice.


• Computer literacy, including constructing a logical search of electronic records.


• Ability to identify potential problems and develop solutions.


• Capable of logically and effectively structuring tasks, setting priorities, and developing/executing long-term plans.



EEO Statement

BWH is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.