Senior Director, Antibody Bioconjugate Discovery - Boston, MA - Permanent
Proclinical Staffing is seeking a Senior Director, of Antibody Bioconjugate Discovery to join an innovative biotech developing next generation neurogenetic medicines. This is a permanent role located in Boston, MA.
Primary Responsibilities:
In this role, you will oversee all aspects of antibody and antibody bioconjugate technology development and drug discovery to develop next generation CNS therapeutics.
Skills & Requirements:
PhD in chemistry, biochemistry, chemical biology, or a related field with 10+ years of industry experience
Demonstrated leadership and management experience with a track record of leading teams and projects to successful endpoints
Deep expertise in antibody/nanobody generation utilizing a wide range of technologies such as hybridoma, phage display, single B-cell screening, etc.
Demonstrated experience developing antibody bioconjugates, bispecific and multi-specific antibody formats for receptor-drive tissue targeting
Familiarity with performing develop ability/manufacturability assessments for selection and optimization of antibodies and antibody formats
Experience using bioinformatics tools for sequence and structure analysis
Proven leadership skills with mentoring and leading teams in therapeutic antibody development
Ability to work collaboratively in a high-paced project team environment, meet deadlines, and prioritize work across multiple projects
Strong written and verbal communication skills
Experience in CNS delivery strongly preferred
The Senior Director will:
Lead efforts in antibody/nanobody development and engineering, including bispecific, single domain, and multi-domain antibodies for non-viral CNS-penetrant therapeutic programs
Utilize multiple strategies for antibody discovery such as hybridoma screening, B-cell screening, phage display to select and optimize top antibody candidates for affinity, transcytosis and other properties
Design and execute protein engineering strategies to deliver developable biologics formats by applying molecular biology, structure-guided, computational, combinatorial/display approaches
Lead and mentor an antibody engineering and molecular biology team of scientists responsible for designing, generating, and characterizing antibody-based therapeutics
Lead technology development in antibody engineering and contribute to broadening Voyager's intellectual property portfolio
Hire, manage and develop a team of scientists/research associates fostering an environment of creativity, a strong work ethic and teamwork
Develop and manage operating budget
If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or m.robinson@proclinical.com.
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.
Proclinical Staffing is an equal opportunity employer.