Sagimet is a clinical-stage biopharmaceutical company developing novel fatty acid synthase (FASN) inhibitors that are designed to target dysfunctional metabolic pathways in diseases resulting from the overproduction of the fatty acid, palmitate. Sagimet's lead drug candidate, denifanstat, is an oral, once-daily pill and selective FASN inhibitor in development for the treatment of NASH, for which there are no treatments currently approved in the United States or Europe. FASCINATE-2, a Phase 2b clinical trial of denifanstat in NASH with liver biopsy-based primary endpoints, was successfully completed with positive results. For additional information about Sagimet, please visit www.sagimet.com.
Position Summary:
Organizes, manages, and analyzes biomarker data in preclinical and clinical studies. Major team contributor in the areas of translational research and diagnostic biomarker development.
Essential Responsibilities:
Apply data analysis tools and programming methods to provide statistical analysis and visualization to generate insights and knowledge in preclinical and clinical studies
Organize data and evaluate data quality of studies
Write, document, and maintain code in R and SQL to transform, standardize and aggregate data to create analysis-ready data sets from raw data
Participate in designing, planning and developing studies
Contribute to development of diagnostic biomarker for clinical use
Responsible for selection and technical monitoring of CROs, including analytical methods and bioanalysis
Manage external resources in a small company environment
Collaborate with R&D and clinical colleagues, member of the development team, present results to various internal and external audiences, and communicate effectively
Education and Experience Requirements:
BS/BA or MS/MA in a scientific discipline and appropriate work experience. PhD in a scientific discipline is preferred
3+ years of work experience in a research and/or development environment is preferred
Strong programing skill and experience in bioinformatics is preferred
Experience in developing diagnostic biomarkers is a plus
Experience in metabolic disease is a plus
Able to build effective working relationships throughout the organization to achieve goals
Maintains knowledge of state-of-the-art principles and theories and possesses advanced knowledge of scientific principles and concepts in field of expertise
Ability to work independently and effectively on cross-functional project teams
Works on complex problems where analysis of situations or data requires an evaluation of intangible variables
Demonstrates potential for a high level of proficiency, creativity, collaboration with others and independent thought process
Proficient with Microsoft Office and data analysis.
Location: SF Bay Area (preferred) or Remote
Compensation
The expected base salary range for this role is $120,000 - $145,000 Compensation will be based on a variety of factors, including experience, qualifications, and internal equity. Sagimet offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Notice to Recruiters/Staffing Agencies
Recruiters and staffing agencies should not contact Sagimet through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with Sagimet prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with Sagimet and Sagimet will not be responsible for any purported fees.