The Associate Medical Director will be joining the Takeda O-DDU Translational Sciences group with the objective of developing enhanced knowledge of the translational process of drug development, with practical working experience at the interface between discovery and development. This will be achieved through a focus on: (1) customized on-the-job training involving the development process as assets grow through discovery and transition into development; (2) priority participation in the Drug Development Curriculum pending renewal of the program for fall 2019 (3) focused leadership development and mentoring from both oncology discovery and development. The position will begin in discovery with a focus to the translational interface between pre-clinical studies moving into early clinical development.
Working on projects at the interface of discovery and development
The individual will initially be based in the discovery translational sciences team but will work on projects moving towards the GPT structure involving clinical development, with planned opportunities to engage with development initiatives.
The participant will be working with the Supervisor who is assigned from the relevant department to oversee and guide the work. This will initially be structured within the Translational Sciences team.
Range of accountabilities in Translational Sciences can include a focus on biomarkers, PK/PD strategy, clinical mechanisms of action, enabling solutions, interfacing with bioinformatics and genomics pre-clinical and clinical data, and working in a matrix, cross-functional team with other line-functions across research and development in the GPT model including Clinical Development, Biostatistics, Regulatory, Clinical Operations, Project Management, and Commercial stakeholders.
Participating in the Drug Development Curriculum
The individual will have priority focus for participation in the Drug Development Curriculum beginning fall 2019, pending the decision to renew the course. The course entails participation in weekly/bi-weekly seminars and additional individual work with literature (reading and critical analysis).
Working with Discovery and Development Mentors
Discovery and Development Mentors will be assigned, allowing the individual to benefit from personalized coaching and mentorship from senior leaders able to provide feedback and expertise relevant to the translational interface between these departments. The participant is expected to establish and maintain a regular working relationship with mentors.
The individual will also be offered the opportunity to participate in targeted development opportunities. The schedule for these will be agreed upon at the time of job commencement and will focus on combining mentoring/leadership as well as support for the transition to industry along with developing an industry-focused knowledge base focused on both discovery/pre-clinical/translational activities and early clinical development activities.
Ongoing evaluation with individual on meeting career goals and development opportunities within discovery-development interface.
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
MD or internationally recognized equivalent, board certified (pr internationally recognized equivalent) in internal medicine or a subspecialty
Established record of research accomplishments (PhD or equivalent degree, list of publications, grants, research awards etc)
Excellent oral and written communication skills, including writing, reviewing and editing scientific documents
Superior interpersonal skills, diplomacy and positive influencing abilities
Ability to work and drive decision-making within a multi-disciplinary, multi-regional, matrix teams
Good fit with Takeda core values and leadership principles
Right attitude (agile, curious, open-minded, “can-do” mindset)
Superior therapeutic area knowledge and solid understanding of emerging research in designated therapeutic area (if applicable)
PhD (or internationally recognized equivalent)
Ability to drive to or fly to various meetings or R&D sites including overnight trips
Ability to spend longer period of time at a different R&D site (weeks or several months)