Scientist at AstraZeneca in Waltham, Massachusetts

Job Description:

Scientist



Do you have expertise in, and passion for Oncology? Would you like to apply your expertise to impact the patient in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!


At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.


Oncology Safety, a global department within the Clinical Pharmacology and Safety Sciences (CPSS) function, is looking for an experienced histology technician to join their teams to develop and advance our portfolio of innovative anti-cancer medicines in Oncology R&D. As an histology technician you will work at the forefront of experimental pathology and safety science, working in a multidisciplinary environment where you will help progress a rich and diverse pipeline which includes small molecules, cutting-edge mAb-based therapeutics, antibody conjugates, next generation cellular and viral therapies.



Job Summary:

We are seeking an outstanding scientist experienced in histology to join our CPSS pathology team. The successful candidate will provide support to the safety assessment of toxicity, pharmacodynamic, and efficacy animal studies in an exciting collaborative team environment. Specific activities for this role include routine histology techniques (tissue processing, embedding, microtomy, and staining) and immunohistochemistry.



Responsibilities:

• Activities include tissue fixation, trimming, dehydration, infiltration, embedding, microtomy, mounting and sectioning of paraffin tissue blocks, preparing high quality microscope slides for pathology assessment.
  
  


• Perform histochemical and immunohistochemical stains on a variety of preclinical study tissues using automated staining platforms (i.e. Ventana).
  
  


• Prepare and maintain all necessary lab instruments and reagents, including stains, alcohols, and paraffins according to proper specifications.
  
  

Requirements/ Qualifications:

• Minimum bachelor's degree in biological sciences
  
  


• >1 year relevant histology experience
  
  


• Ability to manage multiple projects while maintaining high-quality slide production
  
  


• Excellent communication skills, enthusiastic, self-motivating
  
  


• Ability to work and effectively communicate in a local and global team environment
  
  


• Experience with necropsy tissue collection preferred but not required
  
  


• Maintain digital archive of stained slides by scanning and using Aperio eSlide Manager and digital laboratory notebook
  
  

Why AstraZeneca?



At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey!



So, what's next!




Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!




Where can I find out more?



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