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Protein Biotherapeutic Assay Analyst: LC-MS/MS at GlaxoSmithKline

Posted in Science 30+ days ago.

This job brought to you by eQuest

Type: Full-Time
Location: collegeville, Pennsylvania





Job Description:

We are looking for a highly motivated, flexible and experienced scientist to join a team within the Bioanalysis, Immunogenicity and Biomarkers (BIB) department based in Collegeville, PA.  This group is responsible for the method development and validation of protein biotherapeutic and biomarker assays using LC-MS/MS as well as study support for pre-clinical PK/PD/modelling studies and translation of these assays into the clinic.  Data from this group is a key component to understanding molecules in the GSK pipeline; and serves to make early and informed decisions for asset progression within the organization. The successful candidate will independently develop/validate LC-MS/MS methods and support biotherapeutic and biomarker study endpoints in either non-clinical or clinical studies.  

Key Responsibilities:


  • Working with senior Exploratory Biomarker Staff, the person will be responsible for validating bespoke LC-MS/MS methods.

  • Independently providing sample analysis support for non-clinical and clinical studies by delivering high quality data packages working in a GLP/GCP compliant laboratory setting.

  • Handling of human biological samples and performing experimental work in accordance with HBSM, safety and data integrity guidelines

  • Works and communicates effectively with the group and speaks up when necessary. 

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:


  • Bachelors with three years of related experience or Masters with one year of related experience

  • An in-depth knowledge of quantitative protein assay development and an understanding of the drug development process.

  • Strong laboratory skills in assay validation and sample analysis including the ability to work in a GLP/GCP compliant environment.

  • Maintains a disciplined approach, ensuring a relentless focus on quality, compliance, scientific rigor and operational excellence.

  • Attention to detail and effective communication and documentation skills will be expected. 

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Masters degree in a related field

Why GSK?

Our values and expectations are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:


  • Operating at pace and agile decision-making – using evidence and applying judgment to balance pace, rigor and risk.

  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.

  • Continuously looking for opportunities to learn, build skills and share learning.

  • Sustaining energy and well-being

  • Building strong relationships and collaboration, honest and open conversations.

  • Budgeting and cost-consciousness

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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